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  • J.D., Suffolk University Law School, High Technology Law Concentration with Distinction, 2001
  • Ph.D., Boston University School of Medicine, Biochemistry, 1997
  • B.A./M.A., Boston University, Biology/Biotechnology, magna cum laude, 1991

Bar Admissions

  • Massachusetts
  • U.S. Patent & Trademark Office

Court Admissions

  • U.S. Court of Appeals, Federal Circuit
  • U.S. District Court, District of Massachusetts

Memberships & Affiliations

American Bar Association

American Intellectual Property Law Association

Boston Bar Association

Boston Patent Law Association

Massachusetts Bar Association

Women Entrepreneurs in Science and Technology

Maria Laccotripe Zacharakis, Ph.D.

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  • T: 617.449.6512
    F: 617.607.9218

Dr. Laccotripe Zacharakis is a partner at McCarter & English and has more than 20 years of experience in intellectual property matters. Dr. Laccotripe Zacharakis focuses on the area of life sciences, especially in the fields of biotechnology, molecular biology, immunology, biochemistry, interfering RNA, microbiology, tissue engineering, molecular diagnostics, protein therapeutics and stem cell therapies. Dr. Laccotripe Zacharakis assists clients in developing and implementing effective IP strategies and building strong patent portfolios that protect and facilitate commercialization of biological and pharmaceutical products, as well as platform technologies. Dr. Laccotripe Zacharakis also assists clients, such as companies and investors, with evaluating intellectual property assets in connection with acquisitions, licensing, collaborations and financing. Dr. Laccotripe Zacharakis has developed world-wide strategies to protect products in the market with multi-billion annual sales, as well as performed the IP due diligence for multiple multi-million dollar transactions.  Dr. Laccotripe Zacharakis represents a broad range of clients, including start-up biotechnology and pharmaceutical companies, established biopharmaceutical corporations and academic institutions. 

Dr. Laccotripe Zacharakis has extensive experience in:

• Patent preparation and worldwide patent prosecution
• Due diligence evaluations of patent portfolios
• Analysis, evaluation and opinions on the patentability of inventions
• Freedom-to-operate assessments
• Patent validity opinions
• Competitive landscape analyses
• Interference proceedings before the Patent Trial and Appeals Board (PTAB)
• Opposition proceedings before the European Patent Office
• Investigating and resolving inventorship disputes
• Involvement in licensing strategies, negotiations, and agreements.

Dr. Laccotripe Zacharakis has also conducted pre-litigation investigations and advised clients on patent infringement and ANDA actions under the Hatch-Waxman Act, as well as played an active role in the proceedings when they matured beyond the investigatory stage.

Dr. Laccotripe Zacharakis has been recognized as a Massachusetts Rising Star for 2006-2009 and 2011-2012 and Managing IP’s Top 250 Women in IP in 2014. Super Lawyers is published by Thomson Reuters. Click here for their methodology. No aspect of this advertisement has been approved by the Supreme Court of New Jersey.

Representative Matters

Developed patent strategies for pipeline of biopharmaceutical company with first-ever FDA approved RNA Interference therapeutic.
Developed patent strategy and successfully prosecuted worldwide patents covering leading antibody product for big biopharmaceutical corporation.
Represented a publicly traded biotechnology company in a U.S. interference proceeding successfully revoking the opponent's U.S. patent.
Represented a publicly traded biotechnology company in its multi-million acquisition by a big biopharmaceutical corporation.
Represented academic institution spinoff in its multi-million Series A financing round.